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General Information
DRAVP ID DRAVPe00271
Peptide Name p2(gag) peptide[Δ10-14]
Sequence AEAMSQVTN
Sequence Length 9
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism HIV
Assay Protease inhibition assay
Activity
Hemolytic Activity
Cytotoxicity
Binding Target autolysis
Mechanism The peptide blocks the autolysis of HIV-1 virions for the conservation of viral species.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00271
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C37H63N11O16S
Absent amino acids CDFGHIKLPRWY
Common amino acids A
Mass 950.03
Pl 4
Basic residues 0
Acidic residues 1
Hydrophobic residues 3
Net charge -1
Boman Index -1495
Hydrophobicity -25.56
Aliphatic Index 54.44
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Literature Information
Literature 1
Title Blocking of human immunodeficiency virus type-1 virion autolysis by autologous p2(gag) peptide.
Pubmed ID 15113844
Reference J Biochem. 2004 Mar;135(3):447-53.
Author Misumi S, Morikawa Y, Tomonaga M, Ohkuma K, Takamune N, Shoji S.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.