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General Information
DRAVP ID DRAVPe00273
Peptide Name p2(gag) peptide[Δ10-14,S5A]
Sequence AEAMAQVTN
Sequence Length 9
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism HIV
Assay Protease inhibition assay
Activity
Hemolytic Activity
Cytotoxicity
Binding Target autolysis
Mechanism The peptide blocks the autolysis of HIV-1 virions for the conservation of viral species.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00273
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C37H63N11O15S
Absent amino acids CDFGHIKLPRSWY
Common amino acids A
Mass 934.03
Pl 4
Basic residues 0
Acidic residues 1
Hydrophobic residues 4
Net charge -1
Boman Index -974
Hydrophobicity 3.33
Aliphatic Index 65.56
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Literature Information
Literature 1
Title Blocking of human immunodeficiency virus type-1 virion autolysis by autologous p2(gag) peptide.
Pubmed ID 15113844
Reference J Biochem. 2004 Mar;135(3):447-53.
Author Misumi S, Morikawa Y, Tomonaga M, Ohkuma K, Takamune N, Shoji S.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.