General Information
DRAVP ID DRAVPe00304
Peptide Name D70(Derived from Uperin 7.1)
Sequence GWFDVVKHIAKRF
Sequence Length 13
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00304
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C78H115N21O16
Absent amino acids CELMNPQSTY
Common amino acids FKV
Mass 1602.9
Pl 9.99
Basic residues 4
Acidic residues 1
Hydrophobic residues 7
Net charge 3
Boman Index -1536
Hydrophobicity 0
Aliphatic Index 82.31
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 458.33
Polar residues 1
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.