General Information
DRAVP ID DRAVPe00312
Peptide Name Drosocin (insect)
Sequence GKPRPYSPRPTSHPRPIRV
Sequence Length 19
UniProt ID No entry found
Source Drosophila melanogaster
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID 4EZR
Predicted Structure Download DRAVPe00312
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C98H160N34O24
Absent amino acids ACDEFLMNQW
Common amino acids P
Mass 2198.56
Pl 12.01
Basic residues 6
Acidic residues 0
Hydrophobic residues 2
Net charge 6
Boman Index -6950
Hydrophobicity -157.89
Aliphatic Index 35.79
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 82.78
Polar residues 5
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.