To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe00321
Peptide Name Lycotoxin I (spider)
Sequence IWLTALKFLGKHAAKHLAKQQLSKL
Sequence Length 25
UniProt ID No entry found
Source Lycosa carolinensis
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID 7MMM
Predicted Structure Download DRAVPe00321
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C135H223N37O30
Absent amino acids CDEMNPRVY
Common amino acids L
Mass 2844.49
Pl 10.6
Basic residues 7
Acidic residues 0
Hydrophobic residues 13
Net charge 7
Boman Index -619
Hydrophobicity 6.4
Aliphatic Index 125.2
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 229.17
Polar residues 3
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.