General Information
DRAVP ID DRAVPe00322
Peptide Name B1(derived from Aurein 1.2)
Sequence GLFDIIKKIAESW
Sequence Length 13
UniProt ID No entry found
Source Synthetic construct(derived from Aurein 1.2)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00322
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C73H114N16O19
Absent amino acids CHMNPQRTVY
Common amino acids I
Mass 1519.8
Pl 6.07
Basic residues 2
Acidic residues 2
Hydrophobic residues 7
Net charge 0
Boman Index -229
Hydrophobicity 38.46
Aliphatic Index 127.69
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 458.33
Polar residues 2
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.