General Information
DRAVP ID DRAVPe00335
Peptide Name DRS S9r3
Sequence GLRSRIWLWVLLMIWQESNRFKRM
Sequence Length 24
UniProt ID No entry found
Source Synthetic construct(derived from Dermaseptin S9)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00335
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C145H228N42O31S2
Absent amino acids ACDHPTY
Common amino acids LR
Mass 3119.79
Pl 12
Basic residues 5
Acidic residues 1
Hydrophobic residues 11
Net charge 4
Boman Index -4185
Hydrophobicity -8.75
Aliphatic Index 109.58
Half Life
Extinction Coefficient cystines 16500
Absorbance 280nm 717.39
Polar residues 4
Literature Information
Literature 1
Title Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
Pubmed ID 20086159
Reference Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6.
Author Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr.