DRAVP ID  DRAVPe00528

Peptide Name   peptide 11

Sequence  EAIIRILQQLLFIEFRIKRRRRRRRR

Sequence Length  26

UniProt ID  No entry found

Source  Synthetic construct

Target Organism  HIV

Assay  Integrase assay

Activity 

• [Ref.20708407]HIV-1:Inhibition of 3′-processing catalyzed by integrase(IC50=0.05± 0.01 µM);inhibition of strand transfer catalyzed by integrase(IC50=0.01 ± 0.001 µM).

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity 

• No cytotoxicity information or data found in the reference(s) presented in this entry

Binding Target  Integrase

Mechanism  The peptide acts antiviral activity by inhibiting the activity of integrase.

PDB ID  None

Predicted Structure Download  DRAVPe00528

Linear/Cyclic  Linear

N-terminal Modification  Acetylation

C-terminal Modification  Amidation

Other Modification  None

Stereochemistry  L

Literature 1

Title   R

Pubmed ID   3422.14

Reference   C151H266N58O33

Author   CDHKMNPSTVWY

DOI   12.369999999999999