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General Information
DRAVP ID DRAVPe00623
Peptide Name peptide 4(RSV fusion protein(497-515))
Sequence EKINQSLAFIRKSDELLHNV
Sequence Length 20
UniProt ID P03420
Source Synthetic construct(derived from RSV fusion protein)
Activity Information
Target Organism RSV
Assay rHRSV-mCherry inhibition assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target membrane
Mechanism The peptide disrupts the formation of the postfusion six-helix bundle required for viral cell entry.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00623
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C104H172N30O32
Absent amino acids CGMPTWY
Common amino acids L
Mass 2354.69
Pl 6.86
Basic residues 4
Acidic residues 3
Hydrophobic residues 8
Net charge 1
Boman Index -4521
Hydrophobicity -44.5
Aliphatic Index 117
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Literature Information
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.