To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe00709
Peptide Name FM5
Sequence FVFLM
Sequence Length 5
UniProt ID No entry found
Taxon ID None
Source Synthetic construct(derived from the C-terminal sequence of α1-antitrypsin)
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00709
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C34H49N5O6S
Absent amino acids ACDEGHIKNPQRSTWY
Common amino acids F
Mass 655.85
Pl 5.52
Basic residues 0
Acidic residues 0
Hydrophobic residues 4
Net charge 0
Boman Index 1727
Hydrophobicity 310
Aliphatic Index 136
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title Short cyclic peptides derived from the C-terminal sequence of α1-antitrypsin exhibit significant anti-HIV-1 activity.
Pubmed ID 22406118
Reference Bioorg Med Chem Lett. 2012 Apr 1;22(7):2393-5.
Author Jia Q, Jiang X, Yu F, Qiu J, Kang X, Cai L, Li L, Shi W, Liu S, Jiang S, Liu K.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.