General Information
DRAVP ID DRAVPe00723
Peptide Name T1568(FIV envelope protein (725-759))
Sequence WNHGNITLGEWYNQTKDLQQKFYEIIMDIEQNNVQ
Sequence Length 35
UniProt ID P16090
Source Synthetic construct(derived from FIV envelope protein)
Activity Information
Target Organism FIV
Assay plaque-forming assay,RT infectivity assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00723
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C193H285N51O60S
Absent amino acids ACPRS
Common amino acids NQ
Mass 4311.75
Pl 4.5
Basic residues 3
Acidic residues 5
Hydrophobic residues 10
Net charge -2
Boman Index -7452
Hydrophobicity -101.71
Aliphatic Index 75.14
Half Life
Extinction Coefficient cystines 13980
Absorbance 280nm 411.18
Polar residues 11
Literature Information
Literature 1
Title C-Terminal gp40 peptide analogs inhibit feline immunodeficiency virus: cell fusion and virus spread.
Pubmed ID 12186891
Reference J Virol. 2002 Sep;76(18):9079-86.
Author Medinas RJ, Lambert DM, Tompkins WA.