General Information
DRAVP ID DRAVPe00728
Peptide Name T1577(FIV envelope protein (732-766))
Sequence LGEWYNQTKDLQQKFYEIIMDIEQNNVQGKKGIQQ
Sequence Length 35
UniProt ID P16090
Source Synthetic construct(derived from FIV envelope protein)
Activity Information
Target Organism FIV,HIV
Assay plaque-forming assay,RT infectivity assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00728
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C188H292N50O59S
Absent amino acids ACHPRS
Common amino acids Q
Mass 4228.75
Pl 4.94
Basic residues 4
Acidic residues 5
Hydrophobic residues 9
Net charge -1
Boman Index -7758
Hydrophobicity -111.43
Aliphatic Index 75.14
Half Life
Extinction Coefficient cystines 8480
Absorbance 280nm 249.41
Polar residues 9
Literature Information
Literature 1
Title C-Terminal gp40 peptide analogs inhibit feline immunodeficiency virus: cell fusion and virus spread.
Pubmed ID 12186891
Reference J Virol. 2002 Sep;76(18):9079-86.
Author Medinas RJ, Lambert DM, Tompkins WA.