General Information
DRAVP ID DRAVPe00901
Peptide Name T-108
Sequence YDPLVFPSDEFDASISQVNEKINQSLAFIRKSDEL
Sequence Length 35
UniProt ID P69353
Source Synthetic construct(derived from Respiratory syncytial virus(RSV) fusion (F) protein)
Other Link DRAVPa1214
Activity Information
Target Organism RSV
Assay Cytopathic effect(CPE) assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe00901
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C180H276N44O60
Absent amino acids CGHMTW
Common amino acids S
Mass 4016.43
Pl 4.14
Basic residues 3
Acidic residues 7
Hydrophobic residues 13
Net charge -4
Boman Index -7267
Hydrophobicity -40
Aliphatic Index 89.14
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 43.82
Polar residues 8
Literature Information
Literature 1
Title Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.
Pubmed ID 8700906
Reference Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2186-91.
Author Lambert DM, Barney S, Lambert AL, Guthrie K, Medinas R, Davis DE, Bucy T, Erickson J, Merutka G, Petteway SR Jr.