To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01197
Peptide Name B12
Sequence RRKKAVLLALLAP
Sequence Length 13
UniProt ID P08620
Source Synthetic construct(derived from FGF-4 signal sequence)
Activity Information
Target Organism Influenza virus
Assay Hemagglutinin assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism The peptide inhibits influenza virus replication by preventing attachment to cells.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01197
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C67H125N21O14
Absent amino acids CDEFGHIMNQSTWY
Common amino acids L
Mass 1448.86
Pl 12.02
Basic residues 4
Acidic residues 0
Hydrophobic residues 8
Net charge 4
Boman Index -1179
Hydrophobicity 49.23
Aliphatic Index 165.38
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title Identification of the minimal active sequence of an anti-influenza virus peptide.
Pubmed ID 21220525
Reference Antimicrob Agents Chemother. 2011 Apr;55(4):1810-3.
Author Jones JC, Settles EW, Brandt CR, Schultz-Cherry S.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.