General Information
DRAVP ID DRAVPe01201
Peptide Name B8NP
Sequence RRKKALLAVLLALLA
Sequence Length 15
UniProt ID P08620
Source Synthetic construct(derived from FGF-4 signal sequence)
Activity Information
Target Organism Influenza virus
Assay Hemagglutinin assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism The peptide inhibits influenza virus replication by preventing attachment to cells.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01201
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C77H145N23O16
Absent amino acids CDEFGHIMNPQSTWY
Common amino acids L
Mass 1649.14
Pl 12.02
Basic residues 4
Acidic residues 0
Hydrophobic residues 11
Net charge 4
Boman Index -14
Hydrophobicity 116
Aliphatic Index 202
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title Identification of the minimal active sequence of an anti-influenza virus peptide.
Pubmed ID 21220525
Reference Antimicrob Agents Chemother. 2011 Apr;55(4):1810-3.
Author Jones JC, Settles EW, Brandt CR, Schultz-Cherry S.