To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01205
Peptide Name RJ1
Sequence KAKAKAKAKAKAKAKAKAKAK
Sequence Length 21
UniProt ID No entry found
Taxon ID None
Source Synthetic construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HSV
Assay Plaque reduction assay,ELISA
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism The peptide was able to inhibit the entry of HSV-1 into the host cell, probably by blocking heparan sulfate(HS) at the cell surface.
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01205
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C96H184N32O22
Absent amino acids CDEFGHILMNPQRSTVWY
Common amino acids K
Mass 2138.72
Pl 11
Basic residues 11
Acidic residues 0
Hydrophobic residues 10
Net charge 11
Boman Index -4295
Hydrophobicity -118.57
Aliphatic Index 47.62
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title A wide range of medium-sized, highly cationic, alpha-helical peptides show antiviral activity against herpes simplex virus.
Pubmed ID 15498607
Reference Antiviral Res. 2004 Nov;64(2):119-26.
Author Jenssen H, Andersen JH, Mantzilas D, Gutteberg TJ.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.