General Information
DRAVP ID DRAVPe01250
Peptide Name 77-95[94A]
Sequence TDVILMCFSIDSPDSLEAI
Sequence Length 19
UniProt ID P08134
Source Synthetic construct(derived from RhoA protein)
Activity Information
Target Organism RSV
Assay viral antigen reduction assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01250
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C90H145N19O32S2
Absent amino acids GHKNQRWY
Common amino acids DIS
Mass 2069.37
Pl 3.37
Basic residues 0
Acidic residues 4
Hydrophobic residues 8
Net charge -4
Boman Index -868
Hydrophobicity 82.11
Aliphatic Index 123.16
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Literature Information
Literature 1
Title Antiviral activity of RhoA-derived peptides against respiratory syncytial virus is dependent on formation of peptide dimers.
Pubmed ID 14576104
Reference Antimicrob Agents Chemother. 2003 Nov;47(11):3470-7.
Author Budge PJ, Lebowitz J, Graham BS.