General Information
DRAVP ID DRAVPe01290
Peptide Name HR1-a(899-926)
Sequence YENQKQIANQFNKAISQIQESLTTTSTA
Sequence Length 28
UniProt ID P59594
Source Synthetic construct(derived from SARS-CoV spike protein)
Activity Information
Target Organism SARS-CoV
Assay Luciferase assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01290
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C135H218N38O49
Absent amino acids CDGHMPRVW
Common amino acids Q
Mass 3157.44
Pl 6.14
Basic residues 2
Acidic residues 2
Hydrophobic residues 8
Net charge 0
Boman Index -6487
Hydrophobicity -85
Aliphatic Index 66.43
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 55.19
Polar residues 11
Literature Information
Literature 1
Title Fusion core structure of the severe acute respiratory syndrome coronavirus (SARS-CoV): in search of potent SARS-CoV entry inhibitors.
Pubmed ID 18442051
Reference J Cell Biochem. 2008 Aug 15;104(6):2335-47.
Author Chu LH, Chan SH, Tsai SN, Wang Y, Cheng CH, Wong KB, Waye MM, Ngai SM.