To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01291
Peptide Name GST-removed HR2(1145-1192)
Sequence DVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYI
Sequence Length 48
UniProt ID P59594
Source Synthetic construct(derived from SARS-CoV spike protein)
Activity Information
Target Organism SARS-CoV
Assay Luciferase assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01291
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C235H384N62O82
Absent amino acids CFHMPTW
Common amino acids IL
Mass 5390
Pl 4.11
Basic residues 4
Acidic residues 10
Hydrophobic residues 18
Net charge -6
Boman Index -8788
Hydrophobicity -31.67
Aliphatic Index 125.83
Half Life
Extinction Coefficient cystines 2980
Absorbance 280nm 63.4
Polar residues 13
Literature Information
Literature 1
Title Fusion core structure of the severe acute respiratory syndrome coronavirus (SARS-CoV): in search of potent SARS-CoV entry inhibitors.
Pubmed ID 18442051
Reference J Cell Biochem. 2008 Aug 15;104(6):2335-47.
Author Chu LH, Chan SH, Tsai SN, Wang Y, Cheng CH, Wong KB, Waye MM, Ngai SM.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.