General Information
DRAVP ID DRAVPe01331
Peptide Name CL58.d
Sequence managlqllgfilaflgw
Sequence Length 18
UniProt ID No entry found
Source
Activity Information
Target Organism HCV
Assay Pseudoviral particle infection assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target membrane protein
Mechanism The peptide inhibits virus entry in a postbinding step.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry D
Physicochemical Information
Formula H-34O-17
Absent amino acids ACDEFGHIKLMNPQRSTVWY
Common amino acids ACDEFGHIKLMNPQRSTVWY
Mass 1935.36
Pl 5.28
Basic residues 0
Acidic residues 0
Hydrophobic residues 0
Net charge 0
Boman Index 0
Hydrophobicity 0
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title A human claudin-1-derived peptide inhibits hepatitis C virus entry.
Pubmed ID 22378192
Reference Hepatology. 2012 Aug;56(2):507-29.
Author Si Y, Liu S, Liu X, Jacobs JL, Cheng M, Niu Y, Jin Q, Wang T, Yang W.