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General Information
DRAVP ID DRAVPe01435
Peptide Name G154-189(derived from RSV attachment glycoprotein)
Sequence KPPSKPNNDFHFEVFNFVPCSICSNNPTCWAICKRI
Sequence Length 36
UniProt ID P03423
Source Synthetic construct(derived from RSV attachment glycoprotein)
Activity Information
Target Organism RSV
Assay NMR
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01435
Linear/Cyclic Cyclic
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification The peptide formed two disulfide bonds.
Stereochemistry L
Physicochemical Information
Formula C187H278N50O50S4
Absent amino acids GLMQY
Common amino acids NP
Mass 4154.81
Pl 8.52
Basic residues 5
Acidic residues 2
Hydrophobic residues 11
Net charge 3
Boman Index -5371
Hydrophobicity -30.56
Aliphatic Index 51.39
Half Life
Extinction Coefficient cystines 5750
Absorbance 280nm 164.29
Polar residues 13
Literature Information
Literature 1
Title Antiviral activity and structural characteristics of the nonglycosylated central subdomain of human respiratory syncytial virus attachment (G) glycoprotein.
Pubmed ID 11487583
Reference J Biol Chem. 2001 Oct 19;276(42):38988-94.
Author Gorman JJ, McKimm-Breschkin JL, Norton RS, Barnham KJ.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.