General Information
DRAVP ID DRAVPe01451
Peptide Name G154-177[I175A]
Sequence KPPSKPNNDFHFEVFNFVPBSABG
Sequence Length 24
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism RSV
Assay NMR
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01451
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification The 'B' at position 20,23 are S-acetamidomethyl cysteine.
Stereochemistry L
Physicochemical Information
Formula C116H159N29O30
Absent amino acids CILMQRTWY
Common amino acids FP
Mass 2705.05
Pl 6.75
Basic residues 3
Acidic residues 2
Hydrophobic residues 7
Net charge 1
Boman Index -3526
Hydrophobicity -64.58
Aliphatic Index 28.33
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Literature Information
Literature 1
Title Antiviral activity and structural characteristics of the nonglycosylated central subdomain of human respiratory syncytial virus attachment (G) glycoprotein.
Pubmed ID 11487583
Reference J Biol Chem. 2001 Oct 19;276(42):38988-94.
Author Gorman JJ, McKimm-Breschkin JL, Norton RS, Barnham KJ.