General Information
DRAVP ID DRAVPe01453
Peptide Name G154-177[B173A]
Sequence KPPSKPNNDFHFEVFNFVPASIBG
Sequence Length 24
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism RSV
Assay NMR
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01453
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification The 'B' at position 23 is S-acetamidomethyl cysteine.
Stereochemistry L
Physicochemical Information
Formula C122H172N30O32
Absent amino acids CLMQRTWY
Common amino acids FP
Mass 2703.56
Pl 6.75
Basic residues 3
Acidic residues 2
Hydrophobic residues 8
Net charge 1
Boman Index -3034
Hydrophobicity -45.83
Aliphatic Index 44.58
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Literature Information
Literature 1
Title Antiviral activity and structural characteristics of the nonglycosylated central subdomain of human respiratory syncytial virus attachment (G) glycoprotein.
Pubmed ID 11487583
Reference J Biol Chem. 2001 Oct 19;276(42):38988-94.
Author Gorman JJ, McKimm-Breschkin JL, Norton RS, Barnham KJ.