General Information
DRAVP ID DRAVPe01462
Peptide Name G149-177[F168/170A]
Sequence KQRQNKPPSKPNNDFHFEVANAVPBSIBG
Sequence Length 29
UniProt ID No entry found
Source Synthetic construct
Activity Information
Target Organism RSV
Assay NMR
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01462
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification The 'B' at position 25,28 are S-acetamidomethyl cysteine.
Stereochemistry L
Physicochemical Information
Formula C133H203N41O38
Absent amino acids CLMTWY
Common amino acids NP
Mass 3249.66
Pl 9.7
Basic residues 5
Acidic residues 2
Hydrophobic residues 7
Net charge 3
Boman Index -7268
Hydrophobicity -116.21
Aliphatic Index 40.34
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 7
Literature Information
Literature 1
Title Antiviral activity and structural characteristics of the nonglycosylated central subdomain of human respiratory syncytial virus attachment (G) glycoprotein.
Pubmed ID 11487583
Reference J Biol Chem. 2001 Oct 19;276(42):38988-94.
Author Gorman JJ, McKimm-Breschkin JL, Norton RS, Barnham KJ.