General Information
DRAVP ID DRAVPe01519
Peptide Name E6ap18
Sequence IPESSELTLQELLGEERR
Sequence Length 18
UniProt ID No entry found
Source Synthetic construct(derived from E6-associated protein (E6AP))
Activity Information
Target Organism HPV
Assay CD spectroscopy
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target E6 protein
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01519
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C89H151N25O33
Absent amino acids ACDFHKMNVWY
Common amino acids E
Mass 2099.33
Pl 4.33
Basic residues 2
Acidic residues 5
Hydrophobic residues 5
Net charge -3
Boman Index -5326
Hydrophobicity -81.11
Aliphatic Index 108.33
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Literature Information
Literature 1
Title Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus.
Pubmed ID 15182185
Reference Biochemistry. 2004 Jun 15;43(23):7421-31.
Author Liu Y, Liu Z, Androphy E, Chen J, Baleja JD.