General Information
DRAVP ID DRAVPe01520
Peptide Name E6apc1
Sequence YKFACPECPKRFMRSDHLTLHILLHENKK
Sequence Length 29
UniProt ID No entry found
Source Synthetic construct(derived from E6-associated protein (E6AP))
Activity Information
Target Organism HPV
Assay CD spectroscopy
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target E6 protein
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01520
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C160H252N46O40S3
Absent amino acids GQVW
Common amino acids KL
Mass 3556.23
Pl 9.24
Basic residues 9
Acidic residues 3
Hydrophobic residues 8
Net charge 6
Boman Index -6383
Hydrophobicity -69.66
Aliphatic Index 70.69
Half Life
Extinction Coefficient cystines 1615
Absorbance 280nm 57.68
Polar residues 6
Literature Information
Literature 1
Title Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus.
Pubmed ID 15182185
Reference Biochemistry. 2004 Jun 15;43(23):7421-31.
Author Liu Y, Liu Z, Androphy E, Chen J, Baleja JD.