To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01522
Peptide Name E6apn1
Sequence ALQELLGQWLKDGGPSSGRPPPS
Sequence Length 23
UniProt ID No entry found
Source Synthetic construct(derived from E6-associated protein (E6AP))
Activity Information
Target Organism HPV
Assay CD spectroscopy
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target E6 protein
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01522
Linear/Cyclic Linear
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C106H168N30O33
Absent amino acids CFHIMNTVY
Common amino acids GLP
Mass 2390.68
Pl 6.11
Basic residues 2
Acidic residues 2
Hydrophobic residues 6
Net charge 0
Boman Index -2970
Hydrophobicity -72.61
Aliphatic Index 72.17
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 250
Polar residues 7
Literature Information
Literature 1
Title Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus.
Pubmed ID 15182185
Reference Biochemistry. 2004 Jun 15;43(23):7421-31.
Author Liu Y, Liu Z, Androphy E, Chen J, Baleja JD.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.