General Information
DRAVP ID DRAVPe01547
Peptide Name BMAP-18X6X10
Sequence GRFKRXRKKXKKLFKKIS
Sequence Length 18
UniProt ID No entry found
Source Synthetic construct(derived from BMAP-27)
Activity Information
Target Organism HIV
Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01547
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification The 'X' at position 6 and 10 are phenylglycine
Stereochemistry L
Physicochemical Information
Formula C95H166N32O16
Absent amino acids ACDEHMNPQTVWY
Common amino acids K
Mass 2271.26
Pl 12.32
Basic residues 10
Acidic residues 0
Hydrophobic residues 4
Net charge 10
Boman Index -7027
Hydrophobicity -156.11
Aliphatic Index 43.33
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Literature Information
Literature 1
Title Anti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins.
Pubmed ID 18591279
Reference Antimicrob Agents Chemother. 2008 Sep;52(9):3438-40.
Author Wang G, Watson KM, Buckheit RW Jr.