General Information
DRAVP ID DRAVPe01574
Peptide Name TAT(48-57)[G1R]
Sequence RRKKRRQRRR
Sequence Length 10
UniProt ID P04610
Source Synthetic construct
Activity Information
Target Organism HIV
Assay infection inhibition assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism No machanism information found in the reference(s) presented in this entry
Structure Information
PDB ID None
Predicted Structure Download DRAVPe01574
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C59H118N34O12
Absent amino acids ACDEFGHILMNPSTVWY
Common amino acids R
Mass 1495.81
Pl 12.78
Basic residues 9
Acidic residues 0
Hydrophobic residues 0
Net charge 9
Boman Index -12108
Hydrophobicity -428
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title Infection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat.
Pubmed ID 22319541
Reference Int J Pept. 2012;2012:349427.
Author Keogan S, Passic S, Krebs FC.