To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01717
Peptide Name JEV Ep (428–452)
Sequence SIGGVFNSIGRAVHQVFGGAFRTL
Sequence Length 24
UniProt ID P0DOH7
Source Synthetic construct
Activity Information
Target Organism JEV
Assay qRT-PCR, western blotting, the plaque assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target membrane
Mechanism Peptide derived from protein E stem may inhibit virus infection by blocking virus entry.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C113H176N34O30
Absent amino acids CDEKMPWY
Common amino acids G
Mass 2490.85
Pl 12
Basic residues 3
Acidic residues 0
Hydrophobic residues 11
Net charge 3
Boman Index -1191
Hydrophobicity 57.92
Aliphatic Index 93.33
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 9
Literature Information
Literature 1
Title Antiviral activity of peptide inhibitors derived from the protein E stem against Japanese encephalitis and Zika viruses.
Pubmed ID 28232248
Reference Antiviral Res. 2017 May;141:140-149.
Author Chen L, Liu Y, Wang S, Sun J, Wang P, Xin Q, Zhang L, Xiao G, Wang W.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.