General Information
DRAVP ID DRAVPe01759
Peptide Name SARS-CoV-S (1149–1186)
Sequence GDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG
Sequence Length 38
UniProt ID P59594
Source Synthetic construct
Activity Information
Target Organism SARS-CoV
Assay Fusion inhibition assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target GST
Mechanism as GST-fusion polypeptide
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C176H298N50O63
Absent amino acids CFHMPTWY
Common amino acids ILN
Mass 4122.6
Pl 4.2
Basic residues 3
Acidic residues 7
Hydrophobic residues 15
Net charge -4
Boman Index -6614
Hydrophobicity -18.95
Aliphatic Index 130.79
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 11
Literature Information
Literature 1
Title Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors.
Pubmed ID 15158473
Reference Biochem Biophys Res Commun. 2004 Jun 18;319(1):283-8.
Author Zhu J, Xiao G, Xu Y, Yuan F, Zheng C, Liu Y, Yan H, Cole DK, Bell JI, Rao Z, Tien P, Gao GF.