To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01781
Peptide Name m2 /Arg2
Sequence SAVNGQSGRMEFFWTILK
Sequence Length 18
UniProt ID No entry found
Source Synthetic construct(derived from influenza viral HA)
Activity Information
Target Organism Influenza A virus
Assay Infection assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target HA receptor binding domain (RBD)
Mechanism Block the HA–cell interactions by binding to the influenza host cell receptor sialyllactose and thus inhibit the viral entry.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C94H143N25O26S
Absent amino acids CDHPY
Common amino acids FGS
Mass 2071.38
Pl 8.46
Basic residues 2
Acidic residues 1
Hydrophobic residues 7
Net charge 1
Boman Index -2062
Hydrophobicity -6.11
Aliphatic Index 65
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 323.53
Polar residues 6
Literature Information
Literature 1
Title Influenza Viral Hemagglutinin Peptide Inhibits Influenza Viral Entry by Shielding the Host Receptor
Pubmed ID 27623031
Reference ACS Infect Dis. 2016 Mar 11;2(3):187-93
Author Chen Q, Guo Y
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.