To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01806
Peptide Name GI-20D
Sequence gikefkrivqrikdflrnlv
Sequence Length 20
UniProt ID No entry found
Source Synthetic construct(derived from LL-37)
Activity Information
Target Organism EBOV
Assay Plaque assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism Act as CatB inhibitors to block the endosomal processing of EBOV GP, thus preventing virus entry.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Stereochemistry D
Physicochemical Information
Formula H-38O-19
Absent amino acids ACDEFGHIKLMNPQRSTVWY
Common amino acids ACDEFGHIKLMNPQRSTVWY
Mass 2473.01
Pl 11
Basic residues 0
Acidic residues 0
Hydrophobic residues 0
Net charge 0
Boman Index 0
Hydrophobicity 0
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Literature Information
Literature 1
Title Engineered Human Cathelicidin Antimicrobial Peptides Inhibit Ebola Virus Infection.
Pubmed ID 32252021
Reference iScience. 2020 Apr 24;23(4):100999.
Author Yu Y, Cooper CL, Wang G, Morwitzer MJ, Kota K, Tran JP, Bradfute SB, Liu Y, Shao J, Zhang AK, Luo LG, Reid SP, Hinrichs SH, Su K.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.