General Information
DRAVP ID DRAVPe01950
Peptide Name Pep-WAYF
Sequence DHVTPDIAYNPWAYF
Sequence Length 15
UniProt ID No entry found
Source Acacia catechu
Activity Information
Target Organism DENV
Assay Focus-Forming Unit (FFU) Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism the biding of peptide to virus particles might disrupt the ability of the virus to bind to the host cell receptor or possibly block the internalization of the virus into the host cells.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C87H113N19O24
Absent amino acids CEGKLMQRS
Common amino acids ADPY
Mass 1808.97
Pl 4.2
Basic residues 1
Acidic residues 2
Hydrophobic residues 6
Net charge -1
Boman Index -1370
Hydrophobicity -40
Aliphatic Index 58.67
Half Life
Extinction Coefficient cystines 8480
Absorbance 280nm 605.71
Polar residues 4
Literature Information
Literature 1
Title Synthetic Bioactive Peptide Derived from the Asian Medicinal Plant Acacia catechu Binds to Dengue Virus and Inhibits Cell Entry.
Pubmed ID 33172110
Reference Viruses. 2020 Nov 6;12(11):1267.
Author Panya A, Sawasdee N, Songprakhon P, Tragoolpua Y, Rotarayanont S, Choowongkomon K, Yenchitsomanus PT.