To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe01979
Peptide Name SARS-CoV S (483-494), SP-8
Sequence FYTTTGIGYQPY
Sequence Length 12
UniProt ID P59594
Source Synthetic construct
Activity Information
Target Organism SARS-CoV
Assay ELISA
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target ACE2
Mechanism block the binding of S protein to ACE2.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C68H91N13O20
Absent amino acids ACDEHKLMNRSVW
Common amino acids TY
Mass 1410.55
Pl 5.52
Basic residues 0
Acidic residues 0
Hydrophobic residues 2
Net charge 0
Boman Index -389
Hydrophobicity -38.33
Aliphatic Index 32.5
Half Life
Extinction Coefficient cystines 4470
Absorbance 280nm 406.36
Polar residues 8
Literature Information
Literature 1
Title Design and biological activities of novel inhibitory peptides for SARS-CoV spike protein and angiotensin-converting enzyme 2 interaction.
Pubmed ID 16337697
Reference Antiviral Res. 2006 Feb;69(2):70-6.
Author Ho TY, Wu SL, Chen JC, Wei YC, Cheng SE, Chang YH, Liu HJ, Hsiang CY.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.