General Information


DRAVP ID  DRAVPe02017

Peptide Name   E7-type 45

Sequence  TLQEIVLHLEPQNELDPVDLL

Sequence Length  21

UniProt ID  No entry found

Taxon ID  None

Source  Synthetic Construct

Validation   In silico



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not available



Activity Information


Target Organism  HPV

Assay  Not included yet

Activity  No activity information or data found in the reference(s) presented in this entry

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not Available

Mechanism  E5-type 18 (SPATAFTVYVFCFLL) and E7-type 45 (TLQEIVLHLEPQNELDPVDLL) peptides presented the best results for inducing the production of IFN-γ, an essential cytokine in intracellular immunity against HPV infection.



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Not included yet

N-terminal Modification  Not included yet

C-terminal Modification  Not included yet

Other Modification  Not included yet

Stereochemistry  Not included yet



Physicochemical Information


Formula  C109H178N26O36

Absent amino acids  ARCGKMSTYOU

Common amino acids  L

Mass  2428.76

Pl  3.83

Basic residues  0

Acidic residues  5

Hydrophobic residues  12

Net charge  -5

Boman Index  1.02

Hydrophobicity  0.029

Aliphatic Index  157.62

Half Life 

  •     Mammalian:7.2 hours
  •     Yeast:>20 hours
  •     E.coli:>10 hours

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  10



Literature Information


Literature 1

Title   Development of HPV16,18,31,45 E5 and E7 peptides-based vaccines predicted by immunoinformatics tools;

Pubmed ID   31915962

Reference   Biotechnology letters, 42(3), 403–418.;

Author   Namvar, A., Panahi, H. A., Agi, E., & Bolhassani, A. (2020);

DOI   10.1007/s10529-020-02792-6;

Literature 2

Title   Antimicrobial peptides and their potential application in antiviral coating agents

Pubmed ID   35853393

Reference   Colloids and surfaces. B, Biointerfaces, 217, 112693.

Author   Freitas, E. D., Bataglioli, R. A., Oshodi, J., & Beppu, M. M. (2022).

DOI   10.1016/j.colsurfb.2022.112693