General Information
DRAVP ID DRAVPe02017
Peptide Name E7-type 45
Sequence TLQEIVLHLEPQNELDPVDLL
Sequence Length 21
UniProt ID No entry found
Taxon ID None
Source Synthetic Construct
Validation In silico
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not available
Activity Information
Target Organism HPV
Assay Not included yet
Activity No activity information or data found in the reference(s) presented in this entry
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Available
Mechanism E5-type 18 (SPATAFTVYVFCFLL) and E7-type 45 (TLQEIVLHLEPQNELDPVDLL) peptides presented the best results for inducing the production of IFN-γ, an essential cytokine in intracellular immunity against HPV infection.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Not included yet
N-terminal Modification Not included yet
C-terminal Modification Not included yet
Other Modification Not included yet
Stereochemistry Not included yet
Physicochemical Information
Formula C109H178N26O36
Absent amino acids ARCGKMSTYOU
Common amino acids L
Mass 2428.76
Pl 3.83
Basic residues 0
Acidic residues 5
Hydrophobic residues 12
Net charge -5
Boman Index 1.02
Hydrophobicity 0.029
Aliphatic Index 157.62
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 10
Literature Information
Literature 1
Title Development of HPV16,18,31,45 E5 and E7 peptides-based vaccines predicted by immunoinformatics tools;
Pubmed ID 31915962
Reference Biotechnology letters, 42(3), 403–418.;
Author Namvar, A., Panahi, H. A., Agi, E., & Bolhassani, A. (2020);
DOI 10.1007/s10529-020-02792-6;
Literature 2
Title Antimicrobial peptides and their potential application in antiviral coating agents
Pubmed ID 35853393
Reference Colloids and surfaces. B, Biointerfaces, 217, 112693.
Author Freitas, E. D., Bataglioli, R. A., Oshodi, J., & Beppu, M. M. (2022).