General Information


DRAVP ID  DRAVPe02019

Peptide Name   SU2

Sequence  KREHGQHCEF

Sequence Length  10

UniProt ID  None  

Taxon ID  None

Source  Purified from R. paludosa extract

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  HIV-1(RT)

Assay  Plaque reduction assay

Activity 

  • [Ref:17113195]HIV-1:IC50=11µM

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not Available

Mechanism  Not Available



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  C53H79N19O16S1

Absent amino acids  ANDILPSTWVYOU

Common amino acids  EH

Mass  1270.39

Pl  6.92

Basic residues  2

Acidic residues  2

Hydrophobic residues  2

Net charge  0

Boman Index  0.924

Hydrophobicity  -2.04

Aliphatic Index  0

Half Life 

  •     Mammalian:1.3 hours
  •     Yeast:3 mins
  •     E.coli:3 mins

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  7



Literature Information


Literature 1

Title   A peptide with HIV-1 reverse transcriptase inhibitory activity from the medicinal mushroom Russula paludosa

Pubmed ID   17113195

Reference   Peptides, 28(3), 560–565.

Author   Wang, J., Wang, H. X., & Ng, T. B. (2007).

DOI   10.1016/j.peptides.2006.10.004