General Information


DRAVP ID  DRAVPe02022

Peptide Name   CRAMP-1

Sequence  GLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPE

Sequence Length  33

UniProt ID  P51437 

Taxon ID  10090 

Source  Mus musculus(Mouse)

Validation   Experimentally Validated



Origin Information


Gene Name/ID  CAMP(12796)

GenBank  U43409.1

Amino Acid position  135-172

Domain Accession ID  pfam12153 

Nucleotide sequence ID  CM001002.3 

Molecular Type  mRNA

Chromosomal Position  Chromosome 9,(125-172)



Activity Information


Target Organism  HRV,AV

Assay  Not Available

Activity  No activity information or data found in the reference(s) presented in this entry

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not Available

Mechanism  Not Available



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  C173H294N48O44

Absent amino acids  ADCHMSTWYOU

Common amino acids  K

Mass  3750.53

Pl  10.22

Basic residues  9

Acidic residues  3

Hydrophobic residues  12

Net charge  6

Boman Index  1.0286

Hydrophobicity  -0.815

Aliphatic Index  91.52

Half Life 

  •     Mammalian:30 hours
  •     Yeast:>20 hours
  •     E.coli:>10 hours

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  16



Literature Information


Literature 1

Title   Human Cathelicidin (LL-37), a Multifunctional Peptide, is Expressed by Ocular Surface Epithelia and has Potent Antibacterial and Antiviral Activity

Pubmed ID   16020269

Reference   Current eye research, 30(5), 385–394

Author   Gordon, Y. J., Huang, L. C., Romanowski, E. G., Yates, K. A., Proske, R. J., & McDermott, A. M. (2005)

DOI   10.1080/02713680590934111

Literature 2

Title   Cathelicidin antimicrobial peptides suppress EV71 infection via regulating antiviral response and inhibiting viral binding

Pubmed ID   33508330

Reference   Antiviral research, 187, 105021.

Author   Yu, J., Dai, Y., Fu, Y., Wang, K., Yang, Y., Li, M., Xu, W., & Wei, L. (2021)

DOI   10.1016/j.antiviral.2021.105021