General Information
DRAVP ID DRAVPe02030
Peptide Name P9
Sequence CANLLLQYGSFCTQLNRALSGIA
Sequence Length 23
UniProt ID P59594
Taxon ID 694009
Source synthetic Construct (Derived from SARS-CoV: 694009))
Validation Experimentally Validated
Origin Information
Gene Name/ID S2 (918758),
GenBank AY278741.1
Amino Acid position 731-753
Domain Accession ID pfam01601 cd22378
Nucleotide sequence ID AY278741
Molecular Type Genomic RNA
Chromosomal Position N/A
Activity Information
Target Organism SARS-CoV
Assay Syncytia inhibition assay
Activity Not Avaialble
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Spike Protein
Mechanism P9 themselves can markedly inhibit syncytia formation
Structure Information
PDB ID 7SG4
Predicted Structure Download No predicted structure available
Linear/Cyclic Cyclic
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C107H174N30O32S2
Absent amino acids DEHKMPVW
Common amino acids ALCGNQS
Mass 2456.86
Pl 6.72
Basic residues 1
Acidic residues 0
Hydrophobic residues
Net charge 1
Boman Index
Hydrophobicity 0.6
Aliphatic Index 114.78
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 0.606
Polar residues
Literature Information
Literature 1
Title FEBS letters, 579(10), 2130–2136.
Pubmed ID 15811330
Reference Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential
Author Lu, W., Wu, X. D., Shi, M. D., Yang, R. F., He, Y. Y., Bian, C., Shi, T. L., Yang, S., Zhu, X. L., Jiang, W. H., Li, Y. X., Yan, L. C., Ji, Y. Y., Lin, Y., Lin, G. M., Tian, L., Wang, J., Wang, H. X., Xie, Y. H., Pei, G., … Sun, B. (2005).