To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02032
Peptide Name BD-11b
Sequence YKYRYL
Sequence Length 6
UniProt ID No entry found
Taxon ID None
Source S protein of SARS-CoV
Validation Experimentally Validated
Origin Information
Gene Name/ID S1 Protein
GenBank Not Available
Amino Acid position Y438-L443
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV
Assay Cell-cell fusion
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism Block attachment to the host cells
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C45H64N10O10
Absent amino acids ANDCQEGHIMFPSTWVOU
Common amino acids Y
Mass 905.06
Pl 9.53
Basic residues 2
Acidic residues 0
Hydrophobic residues
Net charge 2
Boman Index
Hydrophobicity -1.417
Aliphatic Index 65
Half Life
Extinction Coefficient cystines 4470
Absorbance 280nm 4.939
Polar residues
Literature Information
Literature 1
Title A hexapeptide of the receptor-binding domain of SARS corona virus spike protein blocks viral entry into host cells via the human receptor ACE2
Pubmed ID 22265858
Reference Antiviral research, 94(3), 288–296.
Author Struck, A. W., Axmann, M., Pfefferle, S., Drosten, C., & Meyer, B. (2012)
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.