To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02033
Peptide Name RVFV-6
Sequence WNFFDWFSGLMSWFGGPLK
Sequence Length 19
UniProt ID P03518
Taxon ID 11588
Source Synthetic Construct
Validation Experimentally Validated
Origin Information
Gene Name/ID GP
GenBank P03518
Amino Acid position 450-468
Domain Accession ID pfam19019
Nucleotide sequence ID M11157
Molecular Type Genomic RNA
Chromosomal Position Not Available
Activity Information
Target Organism RVFV, Ebola virus
Assay Not Available
Activity Not Avaialble
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism Fusion inhibitor
Structure Information
PDB ID 4HJ1
Predicted Structure Download No predicted structure available
Linear/Cyclic Cyclic
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C117H148N24O25S1
Absent amino acids ARCQEHITYVOU
Common amino acids GFW
Mass 2322.67
Pl 5.84
Basic residues 1
Acidic residues 1
Hydrophobic residues
Net charge 0
Boman Index
Hydrophobicity 0.142
Aliphatic Index 41.05
Half Life
Extinction Coefficient cystines 16500
Absorbance 280nm 7.104
Polar residues 0
Literature Information
Literature 1
Title A fusion-inhibiting peptide against Rift Valley fever virus inhibits multiple, diverse viruses
Pubmed ID 24069485
Reference PLoS neglected tropical diseases, 7(9), e2430.
Author Koehler, J. W., Smith, J. M., Ripoll, D. R., Spik, K. W., Taylor, S. L., Badger, C. V., Grant, R. J., Ogg, M. M., Wallqvist, A., Guttieri, M. C., Garry, R. F., & Schmaljohn, C. S. (2013).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.