To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02039
Peptide Name Scrambled-2
Sequence KLTILNKDGILRSVILSFN
Sequence Length 19
UniProt ID No entry found
Taxon ID None
Source Synthetic Construct (AVP-p scrambled form)
Validation Experimentally Validated
Origin Information
Gene Name/ID GPC
GenBank Not Available
Amino Acid position Not available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism JUNV
Assay Plaque Reduction Assays
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Membrane
Mechanism Fusion inhibitor, deployment of fusion machinery by the peptide could render virions less able to engage in on-pathway receptor binding or endosomal fusion
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Cyclic
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C98H170N26O27
Absent amino acids ACQEHMPWYOU
Common amino acids IL
Mass 2144.59
Pl 9.99
Basic residues 3
Acidic residues 1
Hydrophobic residues 9
Net charge 2
Boman Index -1499
Hydrophobicity 0.537
Aliphatic Index 158.95
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Literature Information
Literature 1
Title Inhibition of arenavirus infection by a glycoprotein-derived peptide with a novel mechanism
Pubmed ID 24850726
Reference Journal of virology, 88(15), 8556–8564.
Author Spence, J. S., Melnik, L. I., Badani, H., Wimley, W. C., & Garry, R. F. (2014).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.