General Information


DRAVP ID  DRAVPe02058

Peptide Name   Peptide-3

Sequence  DHVTPDIAYNPWAFY

Sequence Length  15

UniProt ID  No entry found

Taxon ID  None

Source  Acacia catechu extract

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  DENV

Assay  Foci-forming unit (FFU) assay

Activity  No activity information or data found in the reference(s) presented in this entry

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not Available

Mechanism  Not Available



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Not included yet

N-terminal Modification  Not included yet

C-terminal Modification  Not included yet

Other Modification  Not included yet

Stereochemistry  Not included yet



Physicochemical Information


Formula  C87H113N19O24

Absent amino acids  RCQEGLKMSOU

Common amino acids  ADPY

Mass  1808.97

Pl  4.2

Basic residues  0

Acidic residues  2

Hydrophobic residues  11

Net charge  -2

Boman Index  0.9743

Hydrophobicity  -0.4

Aliphatic Index  58.67

Half Life 

  •     Mammalian:1.1 hours
  •     Yeast:3 mins
  •     E.coli:>10 hours

Extinction Coefficient cystines  8480

Absorbance 280nm  4.688

Polar residues  14



Literature Information


Literature 1

Title   Novel bioactive peptides demonstrating anti-dengue virus activity isolated from the Asian medicinal plant Acacia Catechu

Pubmed ID   30225997

Reference   Chemical biology & drug design, 93(2), 100–109.

Author   Panya, A., Yongpitakwattana, P., Budchart, P., Sawasdee, N., Krobthong, S., Paemanee, A., Roytrakul, S., Rattanabunyong, S., Choowongkomon, K., & Yenchitsomanus, P. T. (2019). 

DOI   10.1111/cbdd.13407