To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02071
Peptide Name Brevicillin
Sequence SDSVVSDIICTTFCSVTWCQSNCC
Sequence Length 24
UniProt ID J2FTU4
Taxon ID 2825881
Source Brevibacillus
Validation Experimentally Validated
Origin Information
Gene Name/ID PMI05_05757
GenBank EJL20520.1
Amino Acid position 20-43
Domain Accession ID Not Available
Nucleotide sequence ID AKIX01000128
Molecular Type Genomic DNA
Chromosomal Position Not Available
Activity Information
Target Organism SARS-CoV-2
Assay Cell Culture-based Assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Not Found
Mechanism Not Found
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C106H165N27O39S5
Absent amino acids AREGHLKMPYOU
Common amino acids CS
Mass 2601.93
Pl 3.56
Basic residues 0
Acidic residues 2
Hydrophobic residues 18
Net charge -2
Boman Index 0.86
Hydrophobicity 0.662
Aliphatic Index 68.75
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 2.114
Polar residues 24
Literature Information
Literature 1
Title Brevicillin, a novel lanthipeptide from the genus Brevibacillus with antimicrobial, antifungal, and antiviral activity
Pubmed ID 36914211
Reference Journal of applied microbiology, 134(3), lxad054.
Author Singh, S. S., Sharma, D., Singh, C., Kumar, S., Singh, P., Sharma, A., Das, D. K., Pinnaka, A. K., Thakur, K. G., Ringe, R. P., & Korpole, S. (2023)
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.