General Information


DRAVP ID  DRAVPe02077

Peptide Name   Chicken AvBD5

Sequence  GLPQDCERRGGFCSHKSCPPGIGRIGLCSKEDFCCRSRWYS

Sequence Length  41

UniProt ID  Q6IV26 

Taxon ID  9031 

Source  Gallus gallus domestic

Validation   Experimentally Validated



Origin Information


Gene Name/ID  GAL5

GenBank  Not Available

Amino Acid position  26-66

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  IBV

Assay  ELISA

Activity  Not Available

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not Found

Mechanism  Not Found



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  C193H300N62O57S6

Absent amino acids  ANMVOU

Common amino acids  CG

Mass  4593.25

Pl  8.67

Basic residues  7

Acidic residues  4

Hydrophobic residues  24

Net charge  3

Boman Index  2.5

Hydrophobicity  -0.663

Aliphatic Index  38.05

Half Life 

  •     Mammalian:30 hours
  •     Yeast:>20 hours
  •     E.coli:>10 hours

Extinction Coefficient cystines  6990

Absorbance 280nm  1.603

Polar residues  32



Literature Information


Literature 1

Title   Differential modulation of avian β-defensin and Toll-like receptor expression in chickens infected with infectious bronchitis virus

Pubmed ID   26142390

Reference   Applied microbiology and biotechnology, 99(21), 9011–9024.

Author   Xu, Y., Zhang, T., Xu, Q., Han, Z., Liang, S., Shao, Y., Ma, D., & Liu, S. (2015).

DOI   10.1007/s00253-015-6786-8