To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVP ID DRAVPe02082
Peptide Name PEP 19-4
Sequence GKKYRRFRWKFKGKWFWFG
Sequence Length 19
UniProt ID None
Taxon ID None
Source Synthetic construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism IAV(H7N7,H3N2,H1N1)
Assay Hemagglutination assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus Attachment and Virus-Cell Membrane Fusion
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C132H182N36O21
Absent amino acids ANDCQEHILMPSTVOU
Common amino acids RGKFWY
Mass 2609.13
Pl 11.76
Basic residues 8
Acidic residues 0
Hydrophobic residues 7
Net charge 8
Boman Index 2.68
Hydrophobicity -1.421
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 17990
Absorbance 280nm 6.895
Polar residues 3
Literature Information
Literature 1
Title A new class of synthetic anti-lipopolysaccharide peptides inhibits influenza A virus replication by blocking cellular attachment
Pubmed ID 24486207
Reference Antiviral research, 104, 23–33.
Author Hoffmann, J., Schneider, C., Heinbockel, L., Brandenburg, K., Reimer, R., & Gabriel, G. (2014).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.