General Information
DRAVP ID DRAVPe02083
Peptide Name PEP 19-8D
Sequence GFWFKGKWRFKKYRGGRYKKFRWKGKFWFG
Sequence Length 30
UniProt ID None
Taxon ID None
Source Synthetic construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism H7N7,H3N2,H1N2
Assay Hemagglutination assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus Attachment and Virus-Cell Membrane Fusion
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula C200H276N54O33
Absent amino acids ANDCQEHILMPSTVOU
Common amino acids RGKFWY
Mass 3964.73
Pl 11.64
Basic residues 12
Acidic residues 0
Hydrophobic residues 17
Net charge 12
Boman Index 1.1
Hydrophobicity -1.367
Aliphatic Index 0
Half Life
Extinction Coefficient cystines 24980
Absorbance 280nm 6.301
Polar residues 10
Literature Information
Literature 1
Title A new class of synthetic anti-lipopolysaccharide peptides inhibits influenza A virus replication by blocking cellular attachment
Pubmed ID 24486207
Reference Antiviral research, 104, 23–33.
Author Hoffmann, J., Schneider, C., Heinbockel, L., Brandenburg, K., Reimer, R., & Gabriel, G. (2014).