DRAVP ID  DRAVPe02104

Peptide Name   GLRC_4

Sequence  GCRRLCGRLGRRLCRLLCR

Sequence Length  19

UniProt ID  None  

Taxon ID  None 

Source  De novo designed

Validation   Experimentally validated

Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Found

Target Organism  HIV-1IIIB, HSV-2MS

Assay  Anti-HIV assays

Activity 

• [Ref:Not Available]HSV: EC50=69.3 µg/ml in CEM-SS cells, 64.7 µg/ml in Vero cells

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity 

• TC50: >100 µg/ml in CEM-SS cells, TC50: >100 µg/ml in Vero Cells (HSV)

Binding Target  Not Found

Mechanism  Not Available

PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Not included yet

C-terminal Modification  Not included yet

Other Modification  C2-C18, C6-C14 disulfide linkage

Stereochemistry  L

Literature 1

Title   De Novo Design of Antiviral and Antibacterial Peptides with Varying Loop Structures

Pubmed ID   Not Avaialbe

Reference   Reginald et al. J AIDS Clinic Res 2011, S6

Author   Wang G, Watson KM, Mishra B, Lushnikova T, Buckheit RW Jr. 2015

DOI   10.4172/2155-6113.S2-007