General Information


DRAVP ID  DRAVPe02117

Peptide Name   Ginkbilobin

Sequence  ANTAFVSSAHNTQKIPAGAPFNRNLRAMLADLRQNAAFAG

Sequence Length  40

UniProt ID  P83171 

Taxon ID  3311 

Source  Seeds, Ginkgo biloba, Asia

Validation   Experimentally validated



Origin Information


Gene Name/ID  GNK1

GenBank  Not Available

Amino Acid position  1-40

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Found



Activity Information


Target Organism  HIV

Assay  Inhibition Assay

Activity 

  • [Ref:11118300]HIV: Suppressed HIV-1 reverse transcriptase activity

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Not Found

Mechanism  It suppressed the activity of HIV-1 reverse transcriptase 



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  C183H291N59O54S1

Absent amino acids  CEWYOU

Common amino acids  A

Mass  4213.75

Pl  11.71

Basic residues  4

Acidic residues  1

Hydrophobic residues  24

Net charge  3

Boman Index  1.62

Hydrophobicity  -0.18

Aliphatic Index  71.25

Half Life 

  •     Mammalian:4.4 hours
  •     Yeast:>20 hours
  •     E.coli:>10 hours

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  32



Literature Information


Literature 1

Title   Ginkbilobin, a novel antifungal protein from Ginkgo biloba seeds with sequence similarity to embryo-abundant protein

Pubmed ID   11118300

Reference   Biochemical and biophysical research communications, 279(2), 407–411.

Author   Wang, H., & Ng, T. B. (2000).

DOI   10.1006/bbrc.2000.3929