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General Information
DRAVP ID DRAVPe02136
Peptide Name Asperterrestide A
Sequence 2Abz-A-xiIle-N(Me)Phe(bS-OH)
Sequence Length 3
UniProt ID None
Taxon ID None
Source marine-derived fungus Aspergillus terreus SCSGAF0162.
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism H1N1/H3N2
Assay HIV assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity
Binding Target Not found
Mechanism Not Available
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Cyclic
N-terminal Modification Free
C-terminal Modification Free
Other Modification 2Abz at position 1: 2-Aminobenzoyl (Aromatic modification).D-Ala at position2:D-Alanine (Natural enantiomer of alanine).D-xiIle at position 3:D-X-isoleucine (Modified or non-standard isoleucine).D-N(Me)Phe at position 4:D-N-Methylphenylalanine (Methyl group added to the nitrogen of phenylalanine).bS-OH at position5:b-Sulfhydroxyphenylalanine (Phenylalanine derivative with a hydroxyl group attached to a sulfur atom.
Stereochemistry L
Physicochemical Information
Formula C12H15N5O2
Absent amino acids RNDECQMFPSTWYVOU
Common amino acids A
Mass 480.6 g/mol
Pl 6
Basic residues 0
Acidic residues 0
Hydrophobic residues 4
Net charge 0
Boman Index -0.67
Hydrophobicity 2.65
Aliphatic Index 85
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Literature Information
Literature 1
Title Asperterrestide A, a cytotoxic cyclic tetrapeptide from the marine-derived fungus Aspergillus terreus SCSGAF0162
Pubmed ID 23806112
Reference Journal of natural products, 76(6), 1182–1186.
Author He, F., Bao, J., Zhang, X. Y., Tu, Z. C., Shi, Y. M., & Qi, S. H. (2013).
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.